The pathway from glycolysis to oxidative phosphorylation relies on redox-active cofactors and oxidation-reduction reactions at multiple steps. It's operation has a significant effect on the redox state of the cell: the equiLiBrium between the oxidized and reduced states of all of its redox couples. (eg NaD⁺/NADH, thiols such as glutathione). Reactive oxygen species such as peroxide (H₂O₂) and superoxide (O2 x»-) are dangerous at high levels, but recently, cell signalling roles for these species, acting at low concentrations have been revealed. How, explicitly, would such a Warburg Effect-driven signalling role work within tumor cells?